منابع مشابه
Dmd065623 1661..1669
In this study, IC50 shift and time-dependent inhibition (TDI) experimentswere carried out tomeasure the ability of amiodarone (AMIO), and its circulating human metabolites, to reversibly and irreversibly inhibit CYP1A2, CYP2C9, CYP2D6, and CYP3A4 activities in human liver microsomes. The [I]u/Ki,u values were calculated and used to predict in vivo AMIO drug-drug interactions (DDIs) for pharmace...
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Climate in the North Pacific and North American sectors has experienced interdecadal shifts during the twentieth century. A network of recently developed tree-ring chronologies for Southern and Baja California extends the instrumental record and reveals decadal-scale variability back to 1661. The Pacific decadal oscillation (PDO) is closely matched by the dominant mode of tree-ring variability ...
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Safety and availability are issues of major importance in many critical systems. Ensuring simultaneously both attributes is sometimes difficult. Indeed, the introduction of redundancy to increase the overall system availability can lead to safety problems that would not otherwise exist. In this paper, we present a protocol for duplex redundancy management in critical systems that aims to increa...
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ژورنال
عنوان ژورنال: Signótica
سال: 2009
ISSN: 2316-3690,0103-7250
DOI: 10.5216/sig.v2i1.7220